Table 2.
Clinicopathologic factors depending on the distance from the proximal resection margin in patients who underwent curative distal gastrectomy, n (%)
| Variables |
PRM (cm) |
P value | |||||
| ≤ 1.0 (n = 17) | 1.1-3.0 (n = 170) | 3.1-5.0 (n = 287) | > 5.0 (n = 385) | ||||
| Age (yr)1 at operation | 59.7 ± 3.4 | 57.2 ± 1.0 | 58.2 ± 0.7 | 59.0 ± 0.6 | 0.416 | ||
| Sex | 0.279 | ||||||
| Male | 9 (52.9) | 116 (68.2) | 199 (69.3) | 279 (72.5) | |||
| Female | 8 (47.1) | 54 (31.8) | 88 (30.7) | 106 (27.5) | |||
| Tumor location | < 0.001 | ||||||
| Upper 1/3 | 1 (5.9) | 3 (1.8) | 3 (1.0) | 1 (0.3) | |||
| Middle 1/3 | 9 (52.9) | 74 (43.5) | 86 (30.0) | 56 (14.5) | |||
| Lower 1/3 | 7 (41.2) | 93 (54.7) | 198 (69.0) | 328 (85.2) | |||
| Reconstruction | 0.004 | ||||||
| Billroth I | 12 (70.6) | 101 (59.4) | 218 (76.0) | 279 (72.5) | |||
| Billroth II | 3 (17.6) | 32 (18.8) | 38 (13.2) | 64 (16.6) | |||
| RYGJ | 2 (11.8) | 37 (21.8) | 31 (10.8) | 42 (10.9) | |||
| Borrmann type IV | 1 (5.9) | 6 (3.5) | 7 (2.4) | 9 (2.3) | 0.461 | ||
| Tumor size (cm)1 | 6.5 ± 0.8 | 5.8 ± 0.2 | 5.3 ± 0.1 | 5.2 ± 0.1 | 0.004 | ||
| T stage | 0.768 | ||||||
| T2 | 5 (29.4) | 56 (32.9) | 89 (31.0) | 138 (35.8) | |||
| T3 | 7 (41.2) | 75 (44.1) | 123 (42.9) | 165 (42.9) | |||
| T4 | 5 (29.4) | 39 (22.9) | 75 (26.1) | 82 (21.3) | |||
| CLN1 | 26.6 ± 2.0 | 29.3 ± 0.8 | 29.4 ± 0.6 | 28.8 ± 0.5 | 0.612 | ||
| N stage | 0.971 | ||||||
| N0 | 5 (29.4) | 61 (35.9) | 101 (35.2) | 141 (36.6) | |||
| N1 | 2 (11.8) | 36 (21.2) | 63 (22.0) | 80 (20.8) | |||
| N2 | 4 (23.5) | 36 (21.2) | 55 (19.2) | 78 (20.3) | |||
| N3 | 6 (35.3) | 37 (21.8) | 68 (23.7) | 86 (22.3) | |||
| AJCC stage | 0.551 | ||||||
| Stage I | 4 (23.5) | 31 (18.2) | 52 (18.1) | 68 (17.7) | |||
| Stage II | 3 (17.6) | 65 (38.2) | 108 (37.6) | 160 (41.6) | |||
| Stage III | 10 (58.8) | 74 (43.5) | 127 (44.3) | 157 (40.8) | |||
| Differentiation | 0.023 | ||||||
| Differentiated | 4 (23.5) | 64 (37.6) | 105 (36.6) | 178 (46.2) | |||
| Undifferentiated | 13 (76.5) | 106 (62.4) | 182 (63.4) | 207 (53.8) | |||
| LVi | 8 (47.1) | 75 (44.1) | 142 (49.5) | 188 (48.8) | 0.706 | ||
| PNi | 9 (52.9) | 80 (47.1) | 138 (48.1) | 141 (36.6) | 0.010 | ||
| Recurrence | 4 (23.5) | 52 (30.6) | 69 (24.0) | 95 (24.7) | 0.765 | ||
| Local recurrence | 1 (5.9) | 11 (6.5) | 24 (8.4) | 24 (6.2) | 0.727 | ||
1
mean ± standard error. PRM: Proximal resection margin; RYGJ: Roux-en-Y gastrojejunostomy; CLN: Total number of collected lymph nodes; AJCC: American Joint Committee on Cancer; LVi: Lymphovascular invasion; PNi: Perineural invasion.