Table 3.
Multivariable logistic regression analysis of standardised ammonia and lactic acid concentrations in faecal samples for the presence of dementia.
| OR | 95% CI | P | |
|---|---|---|---|
| Model 1 | |||
| st-Ammonia* | 1.7 | 1.1–2.8 | 0.023 |
| st-Lactic acid | 0.3 | 0.02–1.0 | 0.051 |
| Model 2 | |||
| st-Ammonia* | 1.8 | 1.1–3.0 | 0.021 |
| st-Lactic acid | 0.3 | 0.02–1.0 | 0.058 |
| Model 3 | |||
| st-Ammonia* | 1.8 | 1.1–3.1 | 0.023 |
| st-Lactic acid | 0.4 | 0.02–1.2 | 0.125 |
| Enterotype I | 0.5 | 0.1–1.8 | 0.258 |
| F/B ratio | 1.2 | 1.0–1.5 | 0.124 |
| Model 4 | |||
| st-Ammonia* | 1.8 | 1.1–3.2 | 0.031 |
| st-Lactic acid | 0.4 | 0.02–1.3 | 0.154 |
| Enterotype III | 3.6 | 0.9–16.0 | 0.073 |
| F/B ratio | 1.1 | 0.9–1.4 | 0.270 |
The dependent variable was the prevalence of dementia.
The asterisk indicates statistical significance (P < 0.05).
Model 1: adjusted for age, sex, education years.
Model 2: adjusted for model 1 and the presence of ApoE ε4.
Model 3: adjusted for model 2, enterotype I, and the F/B ratio.
Model 4: adjusted for model 2, enterotype III, and the F/B ratio.
Abbreviations: OR, odds ratio; CI, confidence interval. F/B ratio, Firmicutes/Bacteroidetes ratio.