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. 2020 Feb 28;45(7):1223–1231. doi: 10.1038/s41386-020-0646-7

Table 1.

(a) Characteristics of patients and healthy controlsa and (b) comparison of key patient variables at the acute phase and time of scanningb.

(a) Patients (n = 86) Controls (n = 159) χ2 t (df = 243) p Value
Sex (n) M 34, F 52 M 72, F 87 0.751 0.386
Age (years) 54.5 (15.2) 44.7 (18.5) 1.970 <0.001
Education (years) 13.9 (3.5) 15.6 (2.4) −4.516 <0.001
Total MMSE 28.0 (2.0) 29.3 (1.0) −6.778 <0.001
Total CIRS-G 3.6 (3.6) 2.0 (2.0) 4.651 <0.001
(b) Acute Time of scanning t (df = 85) p Value
HAM-D 28.3 (4.6) 5.8 (3.7) 38.245 <0.001
CGI-S 5.1 (0.9) 1.4 (0.7) 31.608 <0.001
Weight (kg) 73.7 (17.9) 81.7 (17.8) −11.213 <0.001
BMI (kg/m2) 26.5 (5.8) 29.3 (5.5) −11.165 <0.001

Mean (SD) unless indicated otherwise.

F female, M male, Total MMSE Mini-Mental State Examination, Total CIRS-G Cumulative Illness Rating Scale-Geriatrics, HAM-D 17 Item Hamilton Depression Rating Scale, CGI-S Clinical Global Impression Severity, BMI body mass index.

aSignificance is reported for two-sample, two-tailed t tests, assuming equal variance.

bSignificance for the comparison of variables at the acute phase to time of scanning is reported for paired, one-tailed t tests, assuming equal variance.