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. 2020 May 12;11:676. doi: 10.3389/fphar.2020.00676

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Copyright © 2020 Cai, Zhu, Wang, Tang, Han, Shu, Zhang, Liang, Ge, Xu, Mei, Zhang and Wei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Etanercept down-regulates clinical indicators (HAQ, SJC, TJC, and DAS28) in patients with RA. (A) Change in the level of TJC scores after etanercept treatment. (B) Change in the level of SJC scores after etanercept treatment. (C) Change in the level of HAQ scores after etanercept treatment. (D) Change in the level of DAS28 scores after etanercept treatment. (E) Treatment with etanercept, the percentage of RA patients who have improved to ACR20 and ACR50 standards. *p < 0.05, **p < 0.01.