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(A) The effect of different concentrations of TNF-α on the proliferation of B cells was detected by CCK-8. (B) The effect of different concentrations of etanercept on the proliferation of B cells stimulated by TNF-α was detected by CCK-8. (C) Expression of TNFRII on type I transitional B cells (CD19+IgM+IgD−), type II transitional B cells (CD19+IgM+IgD+), and mature B cells (CD19+IgD+IgM−) by flow cytometry. ##p < 0.01 vs TNF-α group, **p < 0.01 vs Control group.
