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. 2020 May 12;11:676. doi: 10.3389/fphar.2020.00676

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Copyright © 2020 Cai, Zhu, Wang, Tang, Han, Shu, Zhang, Liang, Ge, Xu, Mei, Zhang and Wei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Etanercept inhibits the transition of transitional B cells to mature B cells. (A) The representative flow cytometry graphs of TNFRII expression on type II transitional B cells in different groups. (B) The expression of TNFRII on type II transitional B cells IS compared between different groups. (C) The representative flow cytometry graphs of mature B cells’ percentage in different groups. (D) Percentage of mature B cells was compared between different groups. *p < 0.05 vs Control group, **p < 0.01 vs Control group, ^#p < 0.05 vs BAFF+TNF-α group, ^##p < 0.01 vs BAFF+TNF-α group.