Table 2.
Short-term effects and correlation with long-term effects.
| A | B | ||||
|---|---|---|---|---|---|
| Cell count [GPt/l], n = 20 | Correlation short-/long-term, n = 19 | ||||
| BL | 6 h | P-value | Spearman r | P-value | |
| Leukocyte | 6.63 | 6.45 | 0.305 | −0.140 | 0.568 |
| Lymphocyte | 1.81 | 1.42 | 0.007 | 0.423 | 0.007 |
| CD3+ | 1.34 | 1.06 | <0.001 | 0.498 | 0.030 |
| CD3+CD4+ | 0.94 | 0.74 | <0.001 | 0.553 | 0.014 |
| CD3+CD8+ | 0.37 | 0.31 | 0.094 | 0.628 | 0.004 |
| CD19+ | 0.26 | 0.19 | <0.001 | 0.501 | 0.029 |
| CD14+ | 0.48 | 0.64 | <0.001 | 0.530 | 0.012 |
| NK cell | 0.16 | 0.18 | 0.658 | 0.613 | 0.005 |
| Neutr. Gran. | 4.15 | 4.12 | 0.920 | 0.535 | 0.018 |
| Heart rate [bpm], n = 20 | |||||
| BL | 6 h | P-value | |||
| 68.95 | 60.05 | 0.001 | |||
(A) Presented are cell counts of different immune cell populations and the heart rate at baseline (BL) and 6 h after start of FTY treatment. Wilcoxon matched pairs test was used to calculate the significance level of the differences (ns, not significant). (B) Presented are spearman r values and p-values as the results of the correlation analysis of the ratio of immunological short- (6 h to baseline) to long-term (month 12 to baseline) FTY treatment effects.