Table 1.
Patient and tumor characteristics.
| Characteristics | n | % | |
|---|---|---|---|
| All patients | 436 | 100 | |
| Sex | |||
| Male | 276 | 63.3 | |
| Female | 160 | 36.7 | |
| Age | |||
| ≤ 65 | 227 | 52.1 | |
| >65 | 209 | 47.9 | |
| Mean, years (SD) | 61.5 (16.2) | ||
| Karnofsky performance status | |||
| ≤ 70 | 142 | 32.6 | |
| >70 | 294 | 67.4 | |
| Mean (SD) | 80 (12.5) | ||
| Preoperative MRI scans | |||
| T1 postcontrast | 436 | 100 | |
| T2-weighted | 346 | 79.4 | |
| T2-weighted FLAIR | 90 | 20.6 | |
| Neurosurgical procedure | |||
| Resection | 340 | 78.0 | |
| Biopsy | 96 | 22.0 | |
| Preoperative volume, median cm3 (IQR) | MGMT promoter | p-value | |
| Methylated 211 (48.4%) | Unmethylated 225(51.6%) | ||
| Contrast-enhancing | 30.1 (39.5) | 35 (45.8) | 0.130 |
| Non-enhancing | 75.5 (105.0) | 65.5 (84.2) | 0.338 |
| Non-enhancing/contrast-enhancing ratio | 2.5 (3.3) | 2.09 (2.6) | 0.045 |
SD, standard deviation; IQR, interquartile range; CE, contrast enhancement; FLAIR fluid-attenuated inversion recovery.