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. 2020 May 12;11:674. doi: 10.3389/fphar.2020.00674

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Copyright © 2020 Rojas-Carvajal, Sequeira-Cordero and Brenes

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Behavioral kinetics in the environmental enrichment cage. Physical activity (A), cage exploration (B), material/items remodeling (C), foraging (D), eating (E), and social interaction (F) displayed over minutes (left panels) and weeks (right panels). Cumulative average activity (G). Data correspond to frequencies expressed as mean ± SEM. CEE, continuous environmental enrichment; REE,restricted and unpredictable environmental enrichment. Single, pairwise-comparisons between groups: *p < .05; **p < .01; ***p < .001. Comparison between behaviors: ⁺⁺⁺ p < .001.