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. 2020 May 12;14:463. doi: 10.3389/fnins.2020.00463

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Copyright © 2020 Fomenko, Lee, McKinnon, Lee, de Snoo, Gondard, Neudorfer, Hamani, Lozano, Kalia and Kalia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Confocal immunofluorescence imaging of representative hippocampal dentate gyrus and striatum adjacent to the virus injection site. Native fluorescence from the repeat stimulation experiment is shown in the three stimulation groups: (A) Control (no stimulation) (B) Theta stimulation (C) Gamma frequency stimulation. The green GFP channel (green) serves as a reporter for transduced hippocampal neurons, whereas the Td Tomato channel (red) shows the transduced cells with concomitant c-Fos expression.