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Axicabtagene ciloleucel (axi-cel or KTE-C19) and tisagenlecleucel (tisa-cel or CTL019) structure. The 2 constructs share identical recognition (FMC63-scFv) and signaling (CD3ζ) domains but the co-stimulatory domains differ: CD28 for axi-cel and 4-1BB for tisa-cel.
