Table 1.

Epidemiology and clinical characteristics of five COVID-19 cases.

	Case 1	Case 2	Case 3	Case 4	Case 5
Gender (M/F)	F	M	M	M	M
Age (y/m)	10 m	5.6 y	8 m	1.2 y	2 m
Exposure history	No	Grandmother confirmed	No	No	Parents and grandparents suspected
First clinical manifestation	Paroxysmal crying, vomiting, currant jelly-like stool	Abdominal pain	Convulsion	Vomiting, diarrhea	Drowsiness and poor feeding, diarrhea
Time from illness onset to fever	30 h	2 days	6 h	5 days	—
Fever at presentation or prior to presentation	At presentation	No	At presentation	At presentation	No
Highest temperature (°C) during the course	39.8	39	38.5	37.9	—
Days from illness onset to admission	1.25	2	0.25	6	3
Underlying or coexisting disease	Intussusception	Acute suppurative appendicitis perforation with localized peritonitis	Traumatic brain injury	Hydronephrosis and stone in the left kidney, rotavirus infection	No
Complications	Shock; MODS (liver, kidney, myocardium, blood coagulation, intestinal); acute respiratory failure	No	No	Acute respiratory failure; acute heart failure; shock; MODS (liver, kidney, myocardium)	Myocardium function damaged
Treatment
Antiviral therapy	Intravenous ribavirin, aerosol inhalation of interferon	Aerosol inhalation of interferon	Intravenous ribavirin, aerosol inhalation of interferon	Intravenous ribavirin, aerosol inhalation of interferon	Aerosol inhalation of interferon
Methylprednisolone	2 mg/(kg·d) × 5d	No	No	2 mg/(kg·d) × 3d	No
Intravenous immunoglobulin	500 mg/(kg·d) × 3d	No	No	500 mg/(kg·d) × 4d	No
Oxygen inhalation	Nasal cannula	No	Nasal cannula	Nasal cannula	No
Invasive mechanical ventilation	Yes	No	No	Yes	No
Blood purification	PE+CRRT	No	No	PE+CRRT	No
Length of stay (days)	36	10	14	17	15
Outcomes	Died	Cured	Cured	Cured	Cured