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. 2020 Mar 28;9(1):16–23. doi: 10.4103/jrpp.JRPP_19_110

Table 3.

Different hemoglobin A1c levels (>7%, >8% and>9%) pre- and post-direct acting antiviral treatment*

HbA1c levels Study groups Mean HbA1c (%)±SD
Mean change in HbA1c±SD Mean difference between groups P*
Pre-index Prior DAA treatment Post-index After DAA treatment
>7% (n=570) Achieved SVR (n=540) 8.4±1.25 7.7±1.28 0.76±1.35 −0.0654 0.7944b
Did not achieve SVR (n=30) 8.5±1.23 7.7±1.05 0.83±1.05
>8% (n=309) Achieved SVR (n=291) 9.3±1.17 8.0±1.50 1.23±1.52 −0.0442 0.9034b
Did not achieve SVR (n=18) 9.3±1.02 8.2+1.14 1.28±1.06
>9% (n=140) Achieved SVR (n=130) 10.2±1.17 8.4±1.81 1.83±1.78 0.4291 0.4562b
Did Not Achieve SVR (n=10) 10.1±0.69 8.7±1.29 1.40±1.29

*P<0.05 was defined as a statistically significant difference between the two groups. The following statistical test was used to calculate the P value: bWilcoxon test was used for continuous variables. Patients are not mutually exclusive since some patients could be in multiple categories. DAA=Direct-acting antiviral, HbA1c=Hemoglobin A1c, HCV=Hepatitis C virus, SVR=Sustained virologic response, SD=Standard deviation