Table 3.
Different hemoglobin A1c levels (>7%, >8% and>9%) pre- and post-direct acting antiviral treatment*
| HbA1c levels | Study groups | Mean HbA1c (%)±SD |
Mean change in HbA1c±SD | Mean difference between groups | P* | |
|---|---|---|---|---|---|---|
| Pre-index Prior DAA treatment | Post-index After DAA treatment | |||||
| >7% (n=570) | Achieved SVR (n=540) | 8.4±1.25 | 7.7±1.28 | 0.76±1.35 | −0.0654 | 0.7944b |
| Did not achieve SVR (n=30) | 8.5±1.23 | 7.7±1.05 | 0.83±1.05 | |||
| >8% (n=309) | Achieved SVR (n=291) | 9.3±1.17 | 8.0±1.50 | 1.23±1.52 | −0.0442 | 0.9034b |
| Did not achieve SVR (n=18) | 9.3±1.02 | 8.2+1.14 | 1.28±1.06 | |||
| >9% (n=140) | Achieved SVR (n=130) | 10.2±1.17 | 8.4±1.81 | 1.83±1.78 | 0.4291 | 0.4562b |
| Did Not Achieve SVR (n=10) | 10.1±0.69 | 8.7±1.29 | 1.40±1.29 | |||
*P<0.05 was defined as a statistically significant difference between the two groups. The following statistical test was used to calculate the P value: bWilcoxon test was used for continuous variables. Patients are not mutually exclusive since some patients could be in multiple categories. DAA=Direct-acting antiviral, HbA1c=Hemoglobin A1c, HCV=Hepatitis C virus, SVR=Sustained virologic response, SD=Standard deviation