Table 3.
Univariate associations between ART exposure and BMD and sclerostin among HIV positive participants.
| Variable (per month) |
Weight bearing bones |
Non-weight bearing bones |
Sclerostin |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lumbar spine |
Total hip |
Femoral Neck |
Distal radius |
Ultradistal radius |
||||||||
| Coefficient (95% CI) |
p-Value | Coefficient (95% CI) |
p-Value | Coefficient (95% CI) |
p-Value | Coefficient (95% CI) |
p-Value | Coefficient (95% CI) |
p-Value | Coefficient (95% CI) |
p-Value | |
| Cumulative PI | −0.02 (−0.09, 0.06) |
0.66 | 0.01 (−0.04, 0.06) |
0.66 | −0.03 (−0.09, 0.02) |
0.24 | −0.04 (−0.09, 0.01) |
0.12 | −0.01 (−0.04, 0.03) |
0.77 | −0.02 (−0.09, 0.06) |
0.66 |
| Cumulative NRTI | −0.03 (−0.10, 0.03) |
0.35 | 0.02 (−0.03, 0.07) |
0.47 | −0.03 (−0.08, 0.02) |
0.26 | −0.04 (−0.08, 0.01) |
0.10 | −0.02 (−0.04, 0.01) |
0.29 | −0.03 (−0.10, 0.03) |
0.35 |
| Cumulative NNRTI | −0.04 (−0.13, 0.05) |
0.37 | −0.03 (−0.09, 0.04) |
0.43 | −0.04 (−0.11, 0.04) |
0.34 | −0.04 (−0.10, 0.03) |
0.27 | −0.02 (−0.07, 0.01) |
0.20 | −0.04 (−0.13, 0.05) |
0.37 |
| Cumulative abacavir | −0.03 (−0.08, 0.03) |
0.32 | 0.02 (−0.2 0.06) |
0.33 | −0.01 (−0.05, 0.05) |
0.96 | −0.01 (−0.05, 0.03) |
0.52 | 0.01 (−0.02, 0.03) |
0.66 | 0.02 (−0.02, 0.06) |
0.38 |
| Cumulative TDF | −0.13 (−0.23,−0.04) |
0.008 | −0.03 (−0.11, 0.04) |
0.37 | −0.07 (−0.15, 0.02) |
0.11 | −0.07 (−0.14, 0.01) |
0.053 | −0.05 (−0.09,−0.01) |
0.043 | −0.13 (−0.23,−0.04) |
0.008 |
Bolded values indicate p<0.05.