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. 2020 Apr 25;39:101005. doi: 10.1016/j.molmet.2020.101005

Figure 5.

Figure 5

Transcriptomic characterization of BAT of adipocyte-specific Beclin1 KO mice. (A) Schematic diagram illustrating the experimental schedule. (B) Heatmap of 3356 mRNA differentially regulated in BAT of adipocyte-specific Beclin1 KO mice from RNA sequencing data (|fold change| ≥ 2, P < 0.05). (C–D) Volume plot and MA-plot of differentially expressed genes in BAT of Beclin1 KO mice (|fold change| ≥ 2, P < 0.05). (E–F) GO analysis of differentially regulated genes. (G–H) Principle component analysis (G) and transcription factor enrichment (H) of differentially regulated genes in BAT of adipocyte-specific Beclin1 KO mice from RNA sequencing data.