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. 2020 Apr 25;39:101005. doi: 10.1016/j.molmet.2020.101005

Figure 7.

Figure 7

Long-term adipocyte-specific Beclin1 KO increases macrophage recruitment and immune responses in adipose tissue. (A) F4/80 staining of paraffin sections of BAT, iWAT, and gWAT of Beclin1 KO and WT mice (size bar = 100 μm). (B) qPCR analysis of Emr1 expression in BAT, iWAT, and gWAT of Beclin1 KO and WT mice. (C) Immunoblot analysis of F4/80, caspase 3, and RIP3 in BAT, iWAT, and gWAT of Beclin1 KO and WT mice. (D) Intraperitoneal glucose tolerance test of Beclin1 KO and WT mice (n = 8 per condition, mean ± SEM, ∗∗P < 0.01, ∗∗∗P < 0.001).