Table 3.

The performance of CM-200 in identifying subjects with suboptimal bone health (DXA T-score < −1).

QUS < −1 vs. T-score < −1
Men								Women
	Sen. (%)	95% CI (%)	Spe. (%)	95% CI (%)	AUC	95% CI	p-Value	Sen. (%)	95% CI (%)	Spe. (%)	95% CI (%)	AUC	95% CI	p-Value
Age
40–50 years	78.6	59.1–91.7	67.8	54.4–79.4	0.732	0.619–0.845	0.001	81.6	65.7–92.3	53.2	41.5–64.7	0.674	0.573–0.776	0.002
51–60 years	57.1	41.0–72.3	50.6	39.5–61.6	0.539	0.432–0.645	0.479	82.5	73.4–89.5	44.1	31.2–57.6	0.633	0.540–0.725	0.006
61 years and above	83.7	74.2–90.8	52.4	41.1–63.6	0.681	0.599–0.763	< 0.001	91.4	84.4–96.0	28.6	15.6–55.3	0.600	0.473–0.727	0.105
Ethnic group
Malay	74.5	60.4–85.7	58.7	48.9–68.1	0.666	0.577–0.755	0.001	90.6	82.95–95.62	48.8	37.9–59.9	0.697	0.619–0.776	< 0.001
Chinese	78.9	69.4–86.6	52.3	41.3–63.2	0.656	0.576–0.737	< 0.001	83.9	76.19–89.86	37.9	25.5–51.6	0.609	0.518–0.700	0.018
Indians/Others	50.0	18.7–81.3	54.8	36.0–72.7	0.524	0.316–0.732	0.82	80.0	56.34–94.27	55.0	31.5–76.9	0.675	0.505–0.845	0.058
BMI
Underweight and Normal	75.9	66.8–83.6	58.2	47.4–68.5	0.671	0.595–0.747	< 0.001	85.8	79.30–90.89	34.4	22.7–47.7	0.601	0.513–0.689	0.021
Overweight	75.0	60.4–86.4	54.1	45.3–62.7	0.645	0.557–0.734	0.003	87.1	78.0–93.36	52.4	42.4–62.4	0.697	0.622–0.773	< 0.001
Overall	75.6	68.1–82.2	55.8	49.0–62.3	0.657	0.602–0.712	<0.001	86.3	81.24–90.34	45.7	37.9–53.7	0.660	0.604–0.716	< 0.001
Overall
	Sen. (%)	95% CI (%)		Spe . (%)	95% CI (%)		AUC	95% CI (%)		p-Value
	82.1	77.9–85.7		51.5	46.5–56.6		0.668	0.630–0.706		< 0.001

Significant p-values are italicized. AUC, area under curve; CI, confidence interval; QUS, quantitative ultrasound; Sen., sensitivity; Spe., specificity