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Complicated immune-related colitis in a 54-year-old man with metastatic melanoma treated first with ipilimumab then with Pembrolizumab. CT image shows mesenteric vessel engorgement (a, yellow arrow); CT performed two months later demonstrates free intraperitoneal air (b,c, red arrow) due to intestinal perforation. © Department of Radiology, Candiolo Cancer Institute—IRCCS. Turin.
