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Hypophysitis in a 54-year-old woman with metastatic melanoma treated with ipilimumab. MRI performed at time of headache shows homogeneously enlarged pituitary gland (a, yellow arrow). Ipilimumab was stopped and patient was given hormone replacement therapy. MRI obtained one month later shows decrease in size of pituitary gland (b, red arrow). © Department of Neuroradiology, University of Pisa.
