. 2020 Mar 27;9(4):62. doi: 10.3390/biology9040062

Table 2.

The 250 differentially expressed genes (DEGs) were identified from three profile datasets, including 228 upregulated genes and 22 downregulated genes in the placenta tissue of preeclampsia compared to normal placenta tissues.

Differentially Expressed Gene	Gene Name
Upregulated	ABCA12, ABCB8, ACAP3, ADAMTSL4, ADM, AHDC1, ANKRD33, ANKRD9, APBA3, LVRN, ARMS2, ARNT2, ARRDC1, ASIC3, AVPI1, BCAR1, BCL9L, BGN, BHLHE40, BIN2, BMP1, BRCA2, BTNL9, ADIRF, C10orf54, C12orf75, C15orf39, NATD1, C1QTNF1, C21orf2, C22orf15, C7orf43, CARD14, CCSAP, CCSER1, CD320, CDC42EP4, CDHR5, CDR2L, CGB1, CGB2, CGB8, CHCHD10, CISH, CLPTM1, CNTNAP3B, COASY, COL17A1, COL7A1, CORO2A, CPZ, CRLF1, CRTC2, CSF3R, DDX43P1, CTDSP1, CYP2J2, CYP51A1P3, DACT2, DDX60L, DIO2, DLGAP4, DLX3, DLX4, DNAH11, DOT1L, DPPA4, ECM1, EHD1, EMC10, EVA1B, FAM109A, FAM160B2, FBLN1, FER1L4, FES, FOXO6, FSTL3, FZR1, GAA, GDPD5, GLTSCR1, GRAMD1A, GRB7, GRINA, GRN, GUSBP3, HID1, HIST1H2AE, HIST1H4C, HIST1H4F, HIST2H2AC, HK2, HPSE, HSD11B2, HSD17B1, HSD17B1P1, HTRA4, IGFBP1, IGHA1, IGHA2, IPMK, IPO13, ITGB4, ITPK1, ITPK1-AS1, KCNC4, KCTD17, KDM6B, KIAA1211, KIAA1522, KLC2, KRT80, LAMC3, LCAT, LDHD, LENG8, LEP, LMO2, LRCH4, LTBP3, LTBR, LYN, MAFK, MAGEA11, MAP1S, MAPRE3, MATN3 MC1R, MEN1, MIR205HG, MKNK2, MTA1, MYO7B, NDRG1, NLGN4X, NOL3, NPHP1, NRIP1, OTUD5, P2RY6, PDK3, PER1, PIGT, PIM3, GSAP, PISD, PLEKHA5, PLEKHA7, PLIN2, PLK3, PLXNA3, PNMT, PRKD3, PTBP3, PTGES2, PTPN23, RAB4B-EGLN2, RAVER1, RELL2, RFX1, RHBDF1, RIN3, RNF44, RTEL1-TNFRSF6B, SASH1, SCAF1, SEMA3F, SERPINB9, SH3BP2, SH3BP5, SH3GLB2, SIGLEC6, SIN3B, SLC16A1, SLC25A35, SLC26A11, SLC2A8, SLC9A1, SLCO3A1 SMOC1, SNCA, SNX8, SP2, SPINT1, SPIRE2, SPON1, SPRY4, SRCIN1, SSH3, ST8SIA4, STX1B, SYMPK, SYNGR1, TCTEX1D4, TEAD3, TET3, THOP1, TKT, TMEM132A, TMEM74B, TMEM8A, TMPRSS6, TNPO2 TPBG, TREM1, TRIM25, TRIM45, TRIM62, TUBB3, UBALD1, UBALD2, ULK1, UPK1B, VAMP2, VIPR1, KMT2B, ZDHHC8P1, ZNF124, ZNF175, ZNF512B, ZNF714, ZNF750, ZNF76, ZNF90, CGB3, PATJ, NECTIN4
Downregulated	ACTA2, CXCL9, CYP1A1, DEFA1, DEFA1B, FCGR3A, HBB, HBG1, HLA-DRA, KRT6A, LGALS14, LOC100129345, LYPD5, LYZ, MAGEA4, NCMAP, PSG10P, RPS17, S100A8, SBSPON, THY1, ZDHHC1

Differentially Expressed Gene

Gene Name

Upregulated

ABCA12, ABCB8, ACAP3, ADAMTSL4, ADM, AHDC1, ANKRD33, ANKRD9, APBA3, LVRN, ARMS2, ARNT2, ARRDC1, ASIC3, AVPI1, BCAR1, BCL9L, BGN, BHLHE40, BIN2, BMP1, BRCA2, BTNL9, ADIRF, C10orf54, C12orf75, C15orf39, NATD1, C1QTNF1, C21orf2, C22orf15, C7orf43, CARD14, CCSAP, CCSER1, CD320, CDC42EP4, CDHR5, CDR2L, CGB1, CGB2, CGB8, CHCHD10, CISH, CLPTM1, CNTNAP3B, COASY, COL17A1, COL7A1, CORO2A, CPZ, CRLF1, CRTC2, CSF3R, DDX43P1, CTDSP1, CYP2J2, CYP51A1P3, DACT2, DDX60L, DIO2, DLGAP4, DLX3, DLX4, DNAH11, DOT1L, DPPA4, ECM1, EHD1, EMC10, EVA1B, FAM109A, FAM160B2, FBLN1, FER1L4, FES, FOXO6, FSTL3, FZR1, GAA, GDPD5, GLTSCR1, GRAMD1A, GRB7, GRINA, GRN, GUSBP3, HID1, HIST1H2AE, HIST1H4C, HIST1H4F, HIST2H2AC, HK2, HPSE, HSD11B2, HSD17B1, HSD17B1P1, HTRA4, IGFBP1, IGHA1, IGHA2, IPMK, IPO13, ITGB4, ITPK1, ITPK1-AS1, KCNC4, KCTD17, KDM6B, KIAA1211, KIAA1522, KLC2, KRT80, LAMC3, LCAT, LDHD, LENG8, LEP, LMO2, LRCH4, LTBP3, LTBR, LYN, MAFK, MAGEA11, MAP1S, MAPRE3, MATN3
MC1R, MEN1, MIR205HG, MKNK2, MTA1, MYO7B, NDRG1, NLGN4X, NOL3, NPHP1, NRIP1, OTUD5, P2RY6, PDK3, PER1, PIGT, PIM3, GSAP, PISD, PLEKHA5, PLEKHA7, PLIN2, PLK3, PLXNA3, PNMT, PRKD3, PTBP3, PTGES2, PTPN23, RAB4B-EGLN2, RAVER1, RELL2, RFX1, RHBDF1, RIN3, RNF44, RTEL1-TNFRSF6B, SASH1, SCAF1, SEMA3F, SERPINB9, SH3BP2, SH3BP5, SH3GLB2, SIGLEC6, SIN3B, SLC16A1, SLC25A35, SLC26A11, SLC2A8, SLC9A1, SLCO3A1
SMOC1, SNCA, SNX8, SP2, SPINT1, SPIRE2, SPON1, SPRY4, SRCIN1, SSH3, ST8SIA4, STX1B, SYMPK, SYNGR1, TCTEX1D4, TEAD3, TET3, THOP1, TKT, TMEM132A, TMEM74B, TMEM8A, TMPRSS6, TNPO2
TPBG, TREM1, TRIM25, TRIM45, TRIM62, TUBB3, UBALD1, UBALD2, ULK1, UPK1B, VAMP2, VIPR1, KMT2B, ZDHHC8P1, ZNF124, ZNF175, ZNF512B, ZNF714, ZNF750, ZNF76, ZNF90, CGB3, PATJ, NECTIN4

Downregulated

ACTA2, CXCL9, CYP1A1, DEFA1, DEFA1B, FCGR3A, HBB, HBG1, HLA-DRA, KRT6A, LGALS14, LOC100129345, LYPD5, LYZ, MAGEA4, NCMAP, PSG10P, RPS17, S100A8, SBSPON, THY1, ZDHHC1