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. 2020 Apr 18;8(4):91. doi: 10.3390/biomedicines8040091

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The change of production of cytokines expressed from the spleen. The spleens were collected from mice at 7 days after T. gondii infection (challenge), which was used for detecting the expression of different cytokines (interleukin (IL)-1β, IL-4, IL-6, IL-12, TNF-α, and INF-γ). (A) IL-1β, IL-6, and TNF-α. (B) INF-γ, IL-4, and IL-12. The groups were divided into three groups as follows: the normal group, the non-immunized group infected with T. gondii (the non-immunized infection group), and the T. gondii infection group immunized with SAG1-VLPs (the immunized infection group).