. 2020 Apr 16;10(4):227. doi: 10.3390/diagnostics10040227

Table 3.

Distribution of E2F1 and MYC expressions (fold change) according to PitNET subtype.

Subtype	E2F1	MYC
Subtype	Mean Fold Change (IQR)
All	2.09 (1.16–3.78)	0.32 (0.11–0.64)
GT	3.03 (2.01–4.03) *	0.17 (0.07–0.41) ^†
fCT	1.32 (1.17–1.90) *	0.59 (0.44–1.02) ^†
sCT	3.45 (1.01–5.00)	0.70 (0.25–1.88) ^†
ST	0.96 (0.69–1.41) *	0.28 (0.13–0.54) ^†
p value	<0.001	0.004

GT: gonadotroph; fCT: functioning corticotroph, IQR: interquartile range, sCT: silent corticotroph, ST: functioning somatotroph). p values: according to Kruskal–Wallis test for differences between PitNET subtypes. * Differences between GT and fCT (p = 0.002) and between GT and ST (p < 0.001). ^† Differences between fCT and ST (p = 0.047), between fCT and GT (p = 0.002), between ST and sCT (p = 0.056), and between sCT and GT (p = 0.009).