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. 2020 May 18;77(8):1–11. doi: 10.1001/jamaneurol.2020.1162

Table 1. Baseline Characteristics of Patients and Control Participants.

Variable Primary cohort Stratification
Inflammatory demyelinating CNS events Inflammatory nondemyelinating CNS events
Control participants Patients Control participants Patients Control participants Patients
Patients, No. 106 106 56 56 50 50
Women, No. (%) 68 (64) 68 (64) 40 (71) 40 (71) 28 (56) 28 (56)
Age at autoimmune disease diagnosis, median (IQR), y 35 (23-46) 36 (25-48) 34 (20-41) 34 (24-43) 36 (26-53) 42 (26-59)
Autoimmune disease, No. (%)
Rheumatoid arthritis 48 (45) 48 (45) 26 (46) 26 (46) 22 (44) 22 (44)
Ankylosing spondylitis 4 (4) 4 (4) 1 (2) 1 (2) 3 (6) 3 (6)
Psoriasis and psoriatic arthritis 21 (20) 21 (20) 12 (21) 12 (21) 9 (18) 9 (18)
Crohn disease 27 (25) 27 (25) 14 (25) 14 (25) 13 (26) 13 (26)
Ulcerative colitis 6 (6) 6 (6) 3 (5) 3 (5) 3 (6) 3 (6)
Disease duration at index date, median (IQR), y 13 (6-22) 12 (5-19) 13 (6-19) 12 (6-19) 15 (8-25) 8 (4-17)

Abbreviations: CNS, central nervous system; IQR, interquartile range.