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. Author manuscript; available in PMC: 2020 May 19.
Published in final edited form as: J Med Primatol. 2019 Oct 1;49(1):26–33. doi: 10.1111/jmp.12438

Table 1.

Summary for PK studies of FX1 in mice and macaques

Drug administered FX1
Measured
Animal species CD-1 mice Indian Rhesus macaque
Dose (mg/kg) 25 25
Route I.P. S.Q.
Parameter
Cmax (nM/mL) 7000 155
Tmax (h) 0.5 2
T1/2 (hr) 9.51 3.37
AUC 0-t, (nM *h/mL) 47300 821.3
Mean, n/time point 3 2