. 2019 Nov 11;11(5):633–637. doi: 10.1021/acsmedchemlett.9b00437

Table 1. Inhibition of hCA I, II, and IX (K_I values nM) Isoforms by 4,4′-Biphenylsulfonamides 1–18 and AAZ as Reference Inhibitor by a Stopped-Flow CO₂ Hydrase Assay¹⁸.

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Mean data from three different assays. SD: standard deviations ranged from ±5% to ±10% of the indicated K_I values.

SI: hCA II selectivity index obtained as ratio between K_Is of the indicated hCA and hCA II K_Is.

From ref (13).

Table 1. Inhibition of hCA I, II, and IX (KI values nM) Isoforms by 4,4′-Biphenylsulfonamides 1–18 and AAZ as Reference Inhibitor by a Stopped-Flow CO2 Hydrase Assay18.