Table 1. Affinities of Compounds 2a–g and 3a–g toward σ1, σ2, and GluN2b Receptors.

^aOnly compounds with highest affinities (<100 nM) were tested in triplicate. For low-affinity compounds, the competition curves were recorded only once (single value), whereas the inhibition of the radioligand binding (shown as %) was assayed at a test compound concentration of 1 μM.

^bNot tested.