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. 2020 Apr 7;11(5):713–719. doi: 10.1021/acsmedchemlett.9b00561

Table 2. IC50 Values of Compounds 15ad, SAHA, and CX-4945 against Four Human Tumor Cell Lines.

  IC50 values (μM)
Cpd LNCaP PC3 MCF-7 A549
15a >100 >100 >100 >100
15b >100 >100 >100 >100
15c 16.31 ± 0.7 40.42 ± 4.4 52.48 ± 10.0 104.73 ± 7.9
15d 66.70 ± 5.0 >100 >100 >100
SAHA 0.69 ± 0.1 2.03 ± 0.1 1.26 ± 0.1 3.14 ± 0.2
CX-4945 6.52 ± 0.6 10.87 ± 0.6 9.41 ± 0.3 11.60 ± 1.8