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. 2020 May 14;15:3415–3431. doi: 10.2147/IJN.S230949

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© 2020 Yuan et al.

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The impact of La₂O₃ NPs and MPs on sperm parameters, levels of testis testosterone, genes and proteins involved in synthesis of testosterone. Changes in sperm count (Aa) and sperm motility percentages (Ab) and sperm survival percentages (Ac) of the mice; (Ba) testis testosterone; (Bb) LH levels; (Bc) FSH levels; (Bd) GnRH levels in the 90 days intragastric exposures. (N=10, mean S.D.). *P <0.05 vs control group. Effects of La₂O₃ NPs and MPs on mRNA expression of StAR, CYP11A1, CYP17A1 and LHR in testes (Ca-d). Effects of La₂O₃ NPs and MPs on protein expression of StAR, CYP11A1, CYP17A1 and LHR (Da-b). β-Actin was used as the internal control. *P<0.05 vs control.