Figure 6.

2354glu suppresses NLRP3 inflammasome activation via blockade of P2X7 receptors in acute alcoholic hepatic steatosis. Expression of P2X7 receptors (P2X7R; a, red) and NLRP3 (b, red) in mouse livers was evaluated by dual immunofluorescence staining combined with F4/80 (green, 200× original magnification). (c) Relative fluorescence intensity of P2X7 receptors and NLRP3 was analysed with Image Pro‐Plus 6.0. All histograms represent the mean ± SD of six independent assays with at least three replicates. ^# P < .05, significantly different from normal group; *P < .05, significantly different from ethanol group