TABLE 2.
Expression profile of NR1I3 (CAR) and NR1I2 (PXR) in areas of the brain
| NR1I3 | NR1I2 | Reference | |
|---|---|---|---|
| Rodent | Cortex (mRNA, protein) | Cortex (mRNA, protein) | (Bauer et al., 2004; Chan et al., 2013; Frye, Koonce, Walf, & Rusconi, 2013; Kajta et al., 2019; Litwa et al., 2016; Narang et al., 2008; Wang et al., 2010) |
| Hippocampus (mRNA, protein) | Hippocampus (mRNA, protein) | ||
| Cortical capillaries (mRNA, protein) | Midbrain (mRNA, protein) | ||
| Cortical capillaries (mRNA, protein) | |||
| Quail | Cerebrum (mRNA) | Cerebrum (mRNA) | (Du et al., 2017; Lin et al., 2018; Xia et al., 2017) |
| Cerebellum (mRNA) | Cerebellum (mRNA) | ||
| Rabbit | Cortex (mRNA) | Cortex (mRNA) | (Marini et al., 2007) |
| Hippocampus (mRNA) | Midbrain (mRNA) | ||
| Hypothalamus (mRNA) | Cerebellum (mRNA) | ||
| Midbrain (mRNA) | |||
| Striatum (mRNA) | |||
| Cerebellum (mRNA) | |||
| Porcine | Cortex (mRNA) | Cortex (mRNA) | (Lemmen, Tozakidis, Bele, & Galla, 2013; Lemmen, Tozakidis, & Galla, 2013; Nannelli et al., 2010; Ott et al., 2009) |
| Cerebellum (mRNA) | Cerebellum (mRNA) | ||
| Midbrain (mRNA) | Midbrain (mRNA) | ||
| Hippocampus (mRNA) | Hippocampus (mRNA) | ||
| Meninges (mRNA) | Meninges (mRNA) | ||
| Cortical capillaries (mRNA, protein) | Cortical capillaries (mRNA, protein) | ||
| Human | Brain tissue a (mRNA) | Brain tissue a (mRNA) | (Chan et al., 2011; Lamba et al., 2004; Miki et al., 2005; Nishimura et al., 2004; Savkur et al., 2003) |
| Caudate nucleus (mRNA) | Cerebrum (mRNA) | ||
| Cortical capillaries (mRNA, protein) | Cortex (mRNA) | ||
| Cerebellum (mRNA) | |||
| Cortical capillaries (mRNA, protein) |
a
Refers to no particular area of the brain.