Fig. 2.

Baicalein is a PR antagonist in Ishikawa PR-B cells. a HRE/Luc of tangeretin alone. b HRE/Luc of tangeretin with 100 nM progesterone (P4). c HRE/Luc of wogonin alone. d HRE/Luc of wogonin with 100 nM P4. e HRE/Luc of baicalein alone. f HRE/Luc of baicalein with 100 nM P4. g Fluorescence polarization competitive binding assay for the PR with progesterone and baicalein. N≥3. Data represent mean ± SEM. Significantly different from 0 μM or control. *P < 0.05; **P < 0.01. Bars without common letter are significantly different. ^a-cP<0.05