Table 5.
Compound subclass | Isolated metabolites | Plasmodial strain (activities) | Plant species (Family), Taxon IDb | Part of the plant studied | Place of harvest (City, Country) | Author, references |
---|---|---|---|---|---|---|
Ergostane phytosterols | 109a, 110a, and 111 | 3D7 (IC50 values range from 11.2 to 22.0 µM) | Antrocaryon klaineanum (Anacardiaceae), NCBI:txid289695 | Stem bark | Mount Kala, Cameroon | Douanla et al. [94] |
W2 ( IC50 values range from 11.2 to 22.0 µM) | ||||||
112 | W2mef (IC50 value = 53.45 µM) | Peperomia vulcanica (Piperaceae), NCBI:txid1719589 | Whole plant | Mount Cameroon, Cameroon | Ngemenya et al. [79] | |
113 | W2 (IC50 value = 153.79 µM) | Polyalthia longifolium var. pendula (Annonaceae), NCBI:txid235806 | Stem | Tikrom, near Kumasi, Ghana | Gbedema et al. [68] | |
113 | W2 (IC50 value = 172.9 µM) | Turraea robusta (Meliaceae), NCBI:txid1899148 | Stem bark | Nairobi, Kenya | Irungu et al. [95] | |
D6 (IC50 value = 68.3 µM) | ||||||
Phytosterol glucosides | 114 to 116 | D6 and W2 (from weak to moderate activities) | Turraea nilotica (Meliaceae), NCBI:txid992803 | Stem bark | Nairobi, Kenya | Irungu et al. [95] |
aCompounds identified for the first time in the cited publications
bIdentification number of the source species, derived from the NCBI Taxonomy database