Table 8.
Summary of other compound classes
| Compound subclass | Isolated metabolites | Plasmodial strain (activities) | Plant species (Family), Taxon IDa | Part of the plant studied | Place of harvest (Locality, Country) | Author, references |
|---|---|---|---|---|---|---|
| Amide | 174 | 3D7 (IC50 value = 39.04 µM) | Zanthoxylum heterophyllum (Rutaceae), NCBI:txid1908418 | Leaves | Langevin, Reunion Island | Ledoux et al. [107] |
| Coumarins | 175 | 3D7 (viability percentage = 101.15) | Diospyros conocarpa (Ebenaceae), NCBI:txid13492 | Leaves, trunk, and roots | Ntouessong and Nkoemvone, Cameroon | Fouokeng et al. [108] |
| 176, 177 and 178 | NF54 (IC50 values vary from 2.17 to 60.09 µM) | Diospyros canaliculata (Ebenaceae), NCBI:txid13492 | Stem bark | Kribi, Cameroon | Lenta et al. [90] | |
| Ester | 179 | NF54 (IC50 value = 42.59 µM) | Erythrina caffra (Papilionaceae), NCBI:txid3842 | Stem bark | Pietermaritzburg, South Africa | Chukwujekwu et al. [106] |
| Lactones | 180 | NF54 (IC50 value = 109.99 µM) | Vangueria infausta spp. infausta (Rubiaceae), NCBI:txid164485 | Roots | Mutale Municipality, Limpopo Province, South Africa | Bapela [109] |
| 181 | D10 (IC50 value = 24.70 µM) | Lippia javanica (Verbenaceae), NCBI:txid925357 | Leaves | Thathe Vondo village, Limpopo Province, South Africa | Ludere et al. [110] | |
| Naphthalene derivatives | 182 and 183 | D6 (IC50 value = 10.52 µM for compound 182) | Kniphofia foliosa (Asphodelaceae), NCBI:txid214838 | Rhizomes | Addis Ababa, Ethiopia | Induli et al. [85] |
| W2 (IC50 value = 6.32 µM for compound 182) | ||||||
| 3D7 (IC50 value = 67.32 µM for compound 183) | ||||||
| 182 | D6 (IC50 value = 10.48 µM) | Kniphofia foliosa (Asphodelaceae), NCBI:txid214838 | Roots | Gedo, Ethiopia | Abdissa n [86] | |
| W2 (IC50 value = 6.28 µM) | ||||||
| Spirobisnaphthalene | 184 | NF54 (IC50 value = 73.28 µM) | Entandrophragma congoense (Meliaceae), NCBI:txid2590899 | Bark | Nkomokui, Cameroon | Happi et al. [101] |
| Xanthones | 185 to 187 | F32/24h (IC50 values range from 1.16 to 70.33 µM) | Allanblackia floribunda (Guttiferae- Clusiaceae), NCBI:txid469914 | Whole plant | Mount Kala, Cameroon | Azebaze et al. [78] |
| F32/72h (from 0.91 to 50.23 µM) | ||||||
| FCM29/24h (from 0.83 to 17.93 µM) | ||||||
| FCM29/24h (from 0.68 to 67.22 µM) |
aIdentification number of the source species, derived from the NCBI Taxonomy database