Table 2. MTT Test on MCF-7, Caco-2, and HFF-1 for Compounds 21, 9, 15, 18, and 19.
IC50 ± SD (μM)a |
|||
---|---|---|---|
compd | MCF-7 | Caco-2 | HFF-1 |
21 | 44 ± 0.3 | 21 ± 0.3 | >100b |
9 | 36 ± 0.2 | 59 ± 0.5 | >100b |
15 | 26 ± 0.4 | 28 ± 0.2 | >100b |
18 | >100b | >100b | >100b |
19 | >100b | >100b | >100b |
Each value is the mean ± SD of at least two experiments performed in quadruplicate.
Cell viability reduction lower than 50% at 100 μM.