Skip to main content
. 2020 Mar 19;11(5):773–782. doi: 10.1021/acsmedchemlett.9b00619

Table 2. Cell-Based Efficacy of 1, 4, and 5 against DENV1-4 Serotypes.

  EC50 (μM)a
Cpds DENV1 DENV2 DENV3 DENV4
1 2.8 ± 0.60 2.1 ± 0.22 2.8 ± 0.51 1.7 ± 0.24
4 7.0 ± 3.50 3.5 ± 0.45 7.8 ± 1.67 6.9 ± 1.95
5 3.2 ± 0.72 2.9 ± 0.35 4.3 ± 2.68 5.9 ± 2.65
a

EC50 is the effective concentration that inhibits 50% virus replication as determined by plaque assay against DENV1–4; data is presented as average ± SD from two independent experiments.