Table 2. Anti-proliferative Effect of mPGES-1 Inhibitors in the A549 Human Cancer Cell Line after 24, 48 or 72 h of Treatment^a.

	IC50 ± SD (μM)
compd	24 h	48 h	72 h
1	98.2 ± 1.5	71.4 ± 1.6	28.5 ± 1.1
3	97.5 ± 2.0	57.5 ± 1.5	18.1 ± 0.8
6	95.0 ± 1.7	63.2 ± 2.1	55.2 ± 1.5
13	98.3 ± 1.9	50.6 ± 2.1	19.2 ± 1.3
CAY10526	98.5 ± 1.6	12.5 ± 0.4	9.1 ± 0.5

^aIC₅₀ (μM) values are given as mean ± S.D. of single determinations obtained in three independent experiments.