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. 2020 May 19;20:442. doi: 10.1186/s12885-020-6635-8

Table 5.

Comparison of physician-reported outcome after RT and PRO (n = 38). In both groups, only new and worsened symptoms after RT are listed

CTCAE grade Physician-reported after RT PRO
1/2 3 4 1/2 3 4
Pain 9 (24%) 16 (42%)
Fatigue 10 (26%) 25 (66%)
Nausea/vomiting 1 4 (11%)
Dermatitis 1 (3%) 4 (11%) 1 (3%)
Hyperpigmentation 2 (5%) 2 (5%)
Edema 4 (11%) 14 (37%)
Osteonecrosis, rib fracture
Sensory deficits 15 (39%) 1 (3%) 1 (3%)
Motor deficits 13 (34%) 2 (5%)
Weight loss 4 (11%) 9 (24%) 1 (3%)
Fibrosis 17 (45%)
Pneumonitis 10 (26%)
Dysphagia 2 (5%) 14 (37%) 1 (3%)
Dyspnea 16 (42%) 18 (47%) 4 (11%) 2 (5%)
Cough 14 (37%) 24 (63%) 1 (3%)
Xerostomia 1 (3%) 22 (58%)
Dysphonia 12 (32%) 1 (3%)

RT Radiotherapy, PRO Patient-reported outcome, CTCAE Common Terminology Criteria for Adverse Events