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. 2020 May 18;20:230. doi: 10.1186/s12872-020-01500-6

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — NET reclassification improvement analysis for NLR or PLR in addition to hs- cTnT or NT-proBNP for perioperative cardiovascular risk stratification. Reclassification tables are shown for patients with MACCE and patients without MACCE. yes: at risk, no: not at risk; Correctly reclassified patients: blue, incorrectly reclassified patients: red. a, b The combination of hs-cTnT or NT-proBNP with PLR > 204.4 did not show reclassification improvement (hs-cTnT: NRI_total = 0.01, p = 0.984; NT-proBNP: NRI_total = 0.07 p = 0.762). c The addition of NLR > 3.1 to hs-cTnT led to an overall improvement by seven correctly reclassified patients in the no MACCE group (NRI_total = 0.23, p = 0.008). d The addition of NLR > 3.1 to NT-proBNP led to the correct reclassification of eight patients in the no MACCE group and overall classification improvement (NRI_total = 0.26, p = 0.005). PLR: Platelet to Lymphocyte Ratio, NLR: Neutrophil to Lymphocyte Ratio, MACCE: major adverse cardiovascular and cerebrovascular events