Table 1.
Patient Characteristics
| Pulmonary Hypertension (n = 78) | Controls (n = 78) | P Value | |
|---|---|---|---|
| Age, yr (range) | 12.0 (0-23) | 11.5 (0-23) | 0.98 |
| Female, n (%) | 52 (66.7%) | 51 (65.4%) | 0.87 |
| Weight, kg | 31.7(15.8-49.5) | 31.4 (18.8-54.8) | 0.53 |
| Height, cm | 134.0 (105.0-160.0) | 138.0 (107.0-162.0) | 0.52 |
| Body Surface Area, m2 | 1.11 (0.68-1.55) | 1.10 (0.74-1.59) | 0.62 |
| Congenital Heart Disease, n (%) | 45 (57.7%) | … | … |
| Atrial Septal Defect, Patent Foramen Ovale | 34 (43.6%) | … | … |
| Ventricular Septal Defect | 8 (10.3%) | … | … |
| Patent Ductus Arteriosus | 12 (15.4%) | … | … |
| Other | 5 (6.4%) | … | … |
| Shunt Present at Catheterization, n (%) | 34 (43.6%) | … | … |
| Pulmonary Hypertension Classification | |||
| Group 1 | 55 (70.5%) | ||
| Idiopathic Pulmonary Arterial Hypertension | 30 (38.5%) | … | … |
| Group II | 0 (0%) | ||
| Group III | 6 (7.7%) | ||
| Group IV | 2 (2.6%) | ||
| Group V | 15 (19.2%) | ||
| World Health Organization Class, n (%) | |||
| Not Available | 18 (23.1%) | … | … |
| I | 24 (30.8%) | … | … |
| II | 26 (33.3%) | … | … |
| III | 9 (11.5%) | … | … |
| IV | 1 (1.3%) | … | … |
| Pulmonary Hypertension Medical Therapy | 72 (92.3%) | … | … |
| Mean Pulmonary Artery Pressure, mm Hg | 31.0 (24.5-43.0) | … | … |
| Mean Pulmonary/Systemic Pressure Ratio | 0.58 (0.39-0.72) | … | … |
| Mean Left Atrial Pressure, mm Hg | 9.0 (7.0-10.0) | … | … |
| Mean Right Atrial Pressure, mm Hg | 7.0 (5.0-8.0) | … | … |
| Cardiac Index, L/min/m2 | 3.25 (2.83-3.77) | … | … |
| Pulmonary/Systemic Flow ratio (Qp:Qs) | 1.00 (1.00-1.00) | … | … |
| Indexed Pulmonary Vascular Resistance, WU·m2 | 6.20 (3.94-10.55) | … | … |
| Pulmonary/Systemic Vascular Resistance Ratio | 0.38 (0.25-0.61) | … | … |
Presented as n (%) or median (interquartile range), unless otherwise noted.