Table 4.

Relationship Between Left Ventricular Shape and Outcome Measures

Outcome Measure	Diastolic Eccentricity Index	P Value	Systolic Eccentricity Index	P Value	Maximum Eccentricity Index	P Value	Diastolic RV:LV Ratio	P Value	Systolic RV:LV Ratio	P Value
Death	3.49 (0.06-212.56)	0.55	1.41 (0.08-25.68)	0.81	1.35 (0.19-9.86)	0.77	7.04 (0.31-236.85)	0.28	2.91 (0.55-15.50)	0.21
Transplant	0.011 (0-999.99)	0.39	0.31 (0.01-58.95)	0.66	0.83 (0.05-14.45)	0.90	0.08 (0-212.34)	0.53	0.74 (0.05-12.93)	0.84
PH Hospitalization	17.77 (1.63-193.84)	0.0183	15.31 (2.73-85.95)	0.0019	5.57 (1.74-17.81)	0.0038	11.14 (1.44-86.26)	0.0209	3.99 (1.39-11.40)	0.0099
Therapy Escalation	8.80 (0.59-131.96)	0.12	4.32 (0.96-19.53)	0.06	5.62 (1.42-22.24)	0.0140	12.27 (0.83-181.80)	0.07	3.99 (1.13-14.14)	0.0321
6MWD	−0.37 (−0.62 - −0.05)	0.0264	−0.24 (−0.53-0.10)	0.16	−0.29 (−0.57-0.04)	0.08	−0.16 (−0.46-0.18)	0.35	−0.14 (−0.45-0.19)	0.41
BNP	0.50 (0.27-0.67)	<0.0001	0.29 (0.04-0.51)	0.0259	0.29 (0.03-0.52)	0.0275	0.45 (0.22-0.64)	0.0003	0.38 (0.13-0.58)	0.0040
NT-Pro BNP	0.50 (0.27-0.67)	<0.0001	0.32 (0.07-0.54)	0.0138	0.35 (0.10-0.56)	0.0074	0.49 (0.26-0.67)	<0.0001	0.43 (0.19-0.63)	0.0008
WHO class	0.45 (0.23-0.63)	0.0002	0.58 (0.38-0.72)	<0.0001	0.62 (0.43-0.75)	<0.0001	0.49 (0.27-0.66)	<0.0001	0.63 (0.45-0.76)	<0.0001

Death, Transplant, PH Hospitalization, and Therapy Escalation were evaluated using logistic regression. Data are presented as odds ratio (95% confidence interval).

6MWD, BNP, pro-BNP, and WHO class were evaluated using Spearman correlation coefficients. Data are presented as correlation coefficient (95% confidence interval).

6MWD = 6-minute walk distance; BNP = brain natriuretic peptide; LV = left ventricle; NT-Pro BNP = N-terminal pro-BNP; PH = pulmonary hypertension; RV = right ventricle; WHO = world health organization.