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. Author manuscript; available in PMC: 2021 Feb 18.
Published in final edited form as: Anal Chem. 2020 Feb 7;92(4):3285–3292. doi: 10.1021/acs.analchem.9b05173

Table 1.

Characteristics of biological extracellular vesicles and other particlesa

particle type diameter (nm) density (g·m−1) mass (MDa)
High density lipoprotein b 5 to 15 1.06 to 1.21 ~0.05 to 0.6
Low density lipoprotein b 18 to 28 1.03- 1.063 ~2 to 7
Very low density lipoprotein b 30 to 80 ~1.006 ~8 to 80
Exomeres c ~30 to 50 0.93 to 1.06 ~8 to 40
Exosomes d 30 to 120 1.12 to 1.21 ~10 to 1200
Microvesicles d 50 to 1000 1.16 ~50 to 4 × 106
Virions d ~30 to ~140 1.16 to 1.18 ~10 to 1000
Casein micelle e 50 to 500 1.06 ~1 to 1000
a

Diameters, densities, and masses are derived from literature data as indicated in the text unless otherwise noted here. In cases where we derive a physical parameter from others we have assumed that particles are spherical.

b

Particle diameters and densities are taken from reference 78.

c

Particle diameter and density values from references 16, 27.

d

The diameters and densities of microvesicles, exosomes and virions are taken from reference 76, 77.

e

Values for casein micelle diameters and densities are taken from reference 48.