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. 2020 May 18;20:431. doi: 10.1186/s12885-020-06823-3

Table 3.

Results of the univariable regression analyses with the WHOQOL-BREF and EORTC QLQ-C30 domains/scales as dependent variables

WHOQOL-BREF EORTC QLQ-C30
General facet Physical health Psychological health Social relationships Environment General Health Status/QoL Physical functioning Role functioning Emotional functioning Cognitive functioning Social functioning
Independent variables β β β β β β β β β β β
Age − 0.168** 0.042 0.032 0.074 0.069 − 0.052 − 0.002 0.045 − 0.074 0.058 0.120
Gendera −0.011 −0.121 − 0.075 0.185** 0.077 −0.114 − 0.218** − 0.185** − 0.039 − 0.163* − 0.105
Marital status: no partner versus having a partnerb −0.078 − 0.101 0.039 0.170** 0.079 − 0.043 − 0.076 − 0.038 − 0.132 − 0.010 − 0.163*
Educational level: low versus highc 0.023 0.029 0.086 0.111 0.170** −0.047 −0.006 − 0.008 0.046 0.214** 0.024
Ethnicity: Caucasian versus other ethnicityd −0.127 −0.023 − 0.103 0.049 0.010 −0.056 − 0.001 −0.018 − 0.034 0.007 − 0.079
Employment: yes versus having no jobe 0.218** 0.203** 0.096 −0.018 0.075 0.257** 0.246** 0.135* 0.120 0.148* 0.182**
ECOG: 0 to 1 versus 2 or higherf −0.220** − 0.301** −0.197** − 0.211** −0.123 − 0.200** −0.311** − 0.319** −0.127 0.012 −0.220**
CES-D −0.534** −0.575** − 0.653** −0.168** − 0.465** −0.589** − 0.482** −0.525** − 0.786** −0.575** − 0.505**
STAI Trait −0.236 − 0.356** −0.518** − 0.225** −0.522** − 0.260** −0.209** − 0.151* −0.597** − 0.341** −0.280**
NEO-FFI neuroticism −0.153* −0.296** − 0.494** −0.230** − 0.389** −0.269** − 0.163* −0.217** − 0.525** −0.276** − 0.231**
NEO-FFI extraversion 0.196** 0.210 0.278** 0.216** 0.209** 0.179** 0.179** 0.137 0.203** 0.016 0.195**
NEO-FFI openness 0.049 −0.132 0.002 0.039 −0.059 − 0.045 −0.114 − 0.155* 0.058 − 0.020 −0.067
NEO-FFI agreeableness 0.051 0.177** 0.163* 0.139 0.198** 0.153* 0.145* 0.135 0.240** 0.140 0.148*
NEO-FFI conscientiousness 0.172** 0.291** 0.314** 0.238** 0.295** 0.242** 0.243** 0.187** 0.181** 0.132 0.292**

*P-values of p ≤ 0.10

**P-values of p ≤ 0.05

aMale is reference

bNo partner is reference

cLow educational level is reference

dOther ethnicity is reference

eNo job is reference

f0 to 1 is reference

CES-D score, STAI trait score and NEO-FFI scale scores represent continuous variables

Abbreviations: β standardized beta,WHOQOL-BREF, World Health Organization Quality of Life-BREF questionnaire, EORTC QLQ-C30 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, ECOG Eastern Cooperative Oncology Group, CES-D Center for Epidemiologic Studies Depression Scale, STAI State Trait Anxiety Inventory, NEO-FFI Neuroticism-Extraversion-Openness Five-Factor Inventory