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. 2020 May 18;20:431. doi: 10.1186/s12885-020-06823-3

Table 5.

Results of the multivariable regression analyses for the EORTC QLQ-C30 (p < 0.05)

Independent variables N B SE β P-value Corrected P-valuea 95% CI for B R2
General Health Status/Quality of Life
 Employment: yes versus no job 116 10.405 4.358 0.183 0.019 0.076

1.764,

19.045

 0.417
 CES-D −2.062 0.314 −0.627 < 0.001 < 0.001

−2.684,

−1.439
Physical functioning
 Employment: no versus having a job 117 10.684 3.885 0.204 0.007 0.021

2.981,

18.386

 0.453
 ECOG: 0 to 1 versus 2 or higher −23.586 5.958 −0.304 < 0.001 < 0.001

−35.398,

−11.775
CES-D −1.357 0.284 −0.449 < 0.001 < 0.001

−1.921,

− 0.793
Role functioning
 ECOG: 0 to 1 versus 2 or higher 120 −30.890 7.975 −0.299 < 0.001 < 0.001

−46.692,

−15.088

 0.414
 CES-D −2.197 0.384 −0.542 < 0.001 < 0.001

− 2.957,

−1.437
 STAI Trait 1.840 0.687 0.295 0.009 0.024

0.479,

3.201
Emotional functioning
 CES-D 117 −2.044 0.222 −0.668 < 0.001 < 0.001

−2.483,

−1.604

 0.655
Cognitive functioning
 Educational level: low versus high 129 9.344 4.060 0.170 0.023 0.069

1.307,

17.382

 0.359
 CES-D −1.572 0.274 −0.536 < 0.001 < 0.001

−2.114,

− 1.030
Social functioning
 Partner status: no partner versus having a partner 116 −12.786 5.817 −0.174 0.030 0.090

−24.318,

−1.253

 0.370
 ECOG: 0 to 1 versus 2 or higher −16.748 7.367 −0.188 0.025 0.090

−31.354,

−2.141
 CES-D −1.394 0.348 −0.401 < 0.001 < 0.001

−2.085,

− 0.704

aBenjamini-Hochberg method was used to correct P-values

Abbreviations: EORTC QLQ-C30, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, N number of patients, B unstandardized beta, SE standard error, β standardized beta, CI confidence interval, R2 explained varriance, CES-D Center for Epidemiologic Studies Depression Scale, ECOG Eastern Cooperative Oncology Group, STAI State Trait Anxiety Inventory