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. 2020 Mar 18;11(5):1022–1027. doi: 10.1021/acsmedchemlett.0c00094

Table 3. Anti-proliferative Activities of Benzofuran-Based Carboxylic Acids 9b, 9e, and 9f against Two Breast Cancer Cell Lines: MCF-7 and MDA-MB-231.

  IC50 (μM)a
Cmp MCF-7 MDA-MB-231
9b NAb 37.60 ± 1.86
9e 14.91 ± 1.04 2.52 ± 0.39
9f 19.70 ± 2.06 11.50 ± 1.05
Dox 1.43 ± 0.12 2.36 ± 0.18
a

IC50 values are the mean ± SD of three separate experiments.

b

NA: Derivatives possessing IC50 value >100 μM.