Table 3. Anti-proliferative Activities of Benzofuran-Based Carboxylic Acids 9b, 9e, and 9f against Two Breast Cancer Cell Lines: MCF-7 and MDA-MB-231.
IC50 (μM)a |
||
---|---|---|
Cmp | MCF-7 | MDA-MB-231 |
9b | NAb | 37.60 ± 1.86 |
9e | 14.91 ± 1.04 | 2.52 ± 0.39 |
9f | 19.70 ± 2.06 | 11.50 ± 1.05 |
Dox | 1.43 ± 0.12 | 2.36 ± 0.18 |
IC50 values are the mean ± SD of three separate experiments.
NA: Derivatives possessing IC50 value >100 μM.