Table 2.
Tubular injury in IGT-RI patients.
| NC | IGT | IGT-RI | T2DM | DKD | p value | |
|---|---|---|---|---|---|---|
| UMA | 5.90 (2.90, 11.15) | 14.30 (7.10, 19.95) * | 49.5 (33.7, 64.60)*# | 19.30 (1.70, 16.60)* | 89.40 (71.23, 193.48)*#△$ | 0.000 |
| NAG | 5.70 (3.20, 8.30) | 7.50 (4.25, 11.50)* | 21.80 (9.52, 26.80)*# | 10.10 (8.35, 16.30)* | 24.009 (14.27, 30.85)*#△$ | 0.000 |
| RBP | 0.30 (0.14, 0.46) | 0.78 (0.35, 1.01)* | 1.47 (1.30, 1.89)*# | 0.94 (0.76, 1.13) * | 1.80 (0.38,8.45)*#$ | 0.000 |
| GAL | 2.40 (1.20, 4.50) | 2.30 (1.20, 4.65) | 3.75 (2.40, 9.62)*# | 3.00 (1.90, 4.40) * | 5.50 (3.65, 9.10)*#△$ | 0.000 |
| β2-MG | 0.06 (0.03, 0.10) | 0.03 (0.00, 0.08) | 0.05 (0.03, 0.09) | 0.04 (0.01, 0.08) | 0.30 (0.10, 2.98)*#△$ | 0.001 |
Data are expressed as median (first quartile, third quartile).
*
: compared with NC, p < 0.05; #: compared with IGT, p < 0.05; △: compared with IGT-RI, p < 0.05; $: compared with T2DM, p < 0.05.
β2-MG, β2-microglobulin; GAL, α–galactosidase; NAG, N-acetyl-β-glucosaminidase; RBP, retinol binding protein; UMA, urine microalbumin; NC, normal control; IGT, impaired glucose tolerance; IGT-RI, IGT-renal injury; T2DM, type 2 diabetes mellitus; DKD, diabetic kidney disease.