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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Mol Cancer Ther. 2019 Sep 12;18(12):2233–2245. doi: 10.1158/1535-7163.MCT-19-0118

Figure 1. Knockout of survivin inhibits primary ovarian tumor growth in an orthotopic ovarian cancer mouse model.

Figure 1.

A. Live animal imaging of primary tumors in ovaries of mice at one month following intrabursally injecting SKOV3 survivin KO and control cells (***p<0.001, n=5). B. Tumors in ovaries of mice were dissected and imaged (*p<0.05, n=5). C. Western blot analysis and comparison of survivin, pSMAD2 and EMT markers in primary ovarian tumors from three different xenografted mice (*p<0.05, **p<0.01).