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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Mol Cancer Ther. 2019 Sep 12;18(12):2233–2245. doi: 10.1158/1535-7163.MCT-19-0118

Figure 2. Knockout of survivin inhibits ovarian tumor metastasis in an orthotopic ovarian cancer mouse model.

Figure 2.

A, B. Metastatic tumors in liver (A) and spleen (B) of xenografted mice were identified by live animal imaging. The maximal bioluminescence intensity was compared between control and survivin knockout mice (**p<0.01, ***p<0.001, n=5). C. H&E staining of metastatic tumors in livers of xenografted mice.