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Polarization-sensitive optical frequency domain imaging (PS-OFDI) of (A1–E1) normal artery, (A2–E2) fibroatheroma, (A3–E3) fibrocalcific plaque, (A4–E4) cholesterol crystals, and (A5–E5) macrophage accumulations with matching histology. Scale bar, 1 mm. ∆n, birefringence; Dep, depolarization; Int, intensity; PSR, Picrosirius red staining; Tri, trichrome staining. Adopted from Villiger et al26 with permission from Elsevier.
