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. 2020 May 12;11:1022. doi: 10.3389/fimmu.2020.01022

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Copyright © 2020 Liang, Wang, Chien, Yarmishyn, Yang, Lai, Luo, Lin, Chen, Chang and Chiou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Human coronavirus infects different types of cells. Left: SARS-CoV can infect alveolar epithelial cells and immune cells but can only replicate in epithelial cells. Middle: MERS-CoV infected and replicated in both alveolar epithelial cells and immune cells. Right: SARS-CoV2: infected lung and damaged lung and immune system.