Table 1.

Immunology differences between SARS-CoV, MERS-CoV, and SARS-CoV-2.

	SARS	MERS	SARS-CoV-2
Infected host cell	Alveolar epithelial cells Monocyte-macrophage Dendritic cells Activated T cells	Alveolar epithelial cells Monocyte-macrophage Dendritic cells Activated T cells	Respiratory epithelial cells T lymphocytes
Suspectable for virus replication	Respiratory epithelial cells	Alveolar epithelial cells Monocyte-macrophage Dendritic cells Activated T cells	Respiratory epithelial cells Unknown
Monocyte-macrophage	Abortive replication Viral protein inhibition	Viral replication Kill monocyte-macrophage	Unknown
Impacts on immune system	Indirectly kill: T cell apoptosis	Viral replication Directly killed T cell	Unknown